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FBP1

Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. [provided by RefSeq, Jul 2008]
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Proximal enterocytes, Proximal tubular cells, Hepatocytes, Macrophages)

Immune cell specificity

Immune cell enhanced (eosinophil)

Cell line specificity

Cell line enhanced (HaCaT, MCF7, OE19, RT4, U-698)

Interaction

Homotetramer.

Molecular function

Allosteric enzyme, Hydrolase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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