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FCER1A
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.
Protein class
FDA approved drug targets
Predicted location
Membrane
Single cell type specificity
Cell type enriched (Langerhans cells)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Cell line enriched (HEL)
Interaction
Tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains.
Molecular function
IgE-binding protein, Receptor
More Types Infomation
Related Diseases
Asthma
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, ELISA, FC, IF, IHC, IP
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- Species Reactivity: Mouse
- Type: Hamster IgG
- Application: FC, FuncS, Neut
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FC, CyTOF®, Neut
- Human Anti-FCER1A Recombinant Antibody (clone CBMalpha8) (FAMAB-0279JF)
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- Derivation: Human phage display Fab library
- Species Reactivity: Human
- Type: Human IgG
- Application: IHC
- Human Anti-FCER1A Recombinant Antibody (clone CBMalpha8); Fab Fragment (FAMAB-0279JF-F(E))
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- Derivation: Human phage display Fab library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FuncS
- Human Anti-FCER1A Recombinant Antibody (clone CBMalpha8); scFv Fragment (FAMAB-0279JF-S(P))
-
- Derivation: Human phage display Fab library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FuncS
-
- Species Reactivity: Human
- Application: WB
- Human Anti-FCER1A Antibody (clone MEDI4212), mRNA (PABL-230-mRNA)
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- Species Reactivity: Human
-
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
-
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Anti-Human FCER1A Recombinant Antibody (TAB-264CL)
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- Species Reactivity: Human
- Type: Antibody
- Mouse Anti-FCER1A Recombinant Antibody (clone 4-9E); Fab Fragment (HPAB-1145-FY-S(P))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-FCER1A Recombinant Antibody (clone 5-1D); Fab Fragment (HPAB-1144-FY-S(P))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-FCER1A Recombinant Antibody (clone 2-3A); Fab Fragment (HPAB-1143-FY-S(P))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-FCER1A Recombinant Antibody (clone 4-12C); Fab Fragment (HPAB-1142-FY-S(P))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-FCER1A Recombinant Antibody (clone 4-9E); scFv Fragment (HPAB-1145-FY-F(E))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-FCER1A Recombinant Antibody (clone 5-1D); scFv Fragment (HPAB-1144-FY-F(E))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-FCER1A Recombinant Antibody (clone 2-3A); scFv Fragment (HPAB-1143-FY-F(E))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-FCER1A Recombinant Antibody (clone 4-12C); scFv Fragment (HPAB-1142-FY-F(E))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-FCER1A Recombinant Antibody (clone 7-2G) (HPAB-1147-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.