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FCER2

The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
FCER2
Protein class

Cancer-related genes, CD markers

Predicted location

Intracellular, Membrane, Secreted (different isoforms)

Single cell type specificity

Cell type enriched (B-cells)

Immune cell specificity

Group enriched (naive B-cell, memory B-cell)

Cell line specificity

Cell line enriched (HDLM-2)

Interaction

Homotrimer.

Molecular function

IgE-binding protein, Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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