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FDFT1

This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]
Protein class

Disease related genes, Enzymes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Basal respiratory cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Group enriched (Daudi, RPMI-8226)

Molecular function

Multifunctional enzyme, Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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