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FEV
This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Enteroendocrine cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HMC-1, SH-SY5Y)
Molecular function
Developmental protein, DNA-binding
More Types Infomation
- Recombinant Anti-Human FEV Antibody scFv Fragment (MOB-2758z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, Neut, FuncS
- Recombinant Anti-Human FEV Antibody Fab Fragment (MOB-2758z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, IF, FuncS
- Recombinant Anti-Human FEV Antibody (MOB-2758z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, Neut, FuncS
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For Research Use Only. Not For Clinical Use.