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FGD3
FGD3 (FYVE, RhoGEF And PH Domain Containing 3) is a Protein Coding gene. Diseases associated with FGD3 include glucocorticoid deficiency 3 and aarskog-scott syndrome. Among its related pathways are Signaling by GPCR and Signaling by Rho GTPases. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and small GTPase binding. An important paralog of this gene is FGD1.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids, NK-cells, Early spermatids, T-cells, dendritic cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HMC-1, Karpas-707, RT4)
Molecular function
Guanine-nucleotide releasing factor
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human, Predicted to work with: Orangutan
- Type: Rabbit IgG
- Application: WB, ICC, IF, FC
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For Research Use Only. Not For Clinical Use.