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FGF22

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants.
Protein class

RAS pathway related proteins

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Horizontal cells, Bipolar cells, Rod photoreceptor cells, Muller glia cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AN3-CA)

Interaction

Interacts with FGFR1 and FGFR2. Interacts with FGFBP1.

Molecular function

Growth factor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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