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FLRT1
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain.
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Inhibitory neurons, Oligodendrocytes, Excitatory neurons, Muller glia cells, Bipolar cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (Karpas-707, SCLC-21H, SH-SY5Y, THP-1)
Interaction
Interacts with FGFR1. Interacts (via extracellular domain) with ADGRL1/LPHN1 and ADGRL3 (via olfactomedin-like domain).
More Types Infomation
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.