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FOXJ1

This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[provided by RefSeq, Sep 2009]
Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Group enriched (Endometrial ciliated cells, Respiratory ciliated cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (BEWO, CAPAN-2)

Molecular function

Activator, DNA-binding

More Types Infomation

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