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FPR2
FPR2 (Formyl Peptide Receptor 2) is a Protein Coding gene. Diseases associated with FPR2 include Prion Disease. Among its related pathways are Akt Signaling and Innate Immune System. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and N-formyl peptide receptor activity. An important paralog of this gene is FPR3.
Protein class
G-protein coupled receptors
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Macrophages, Late spermatids, monocytes, Kupffer cells, Hofbauer cells, Early spermatids)
Immune cell specificity
Immune cell enriched (neutrophil)
Cell line specificity
Cell line enriched (U-937)
Interaction
Interacts with Amyloid-beta protein 42, product of APP; the interaction takes place at the cell surface and the complex is then rapidly internalized. (Microbial infection) Interacts with Staphylococcus aureus protein SSL13; this interaction leads to the activation of neutrophils.
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
- Rabbit Anti-FPR2 Polyclonal Antibody (MRO-1875-CN) (MRO-1875-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IHC, FC
- Rabbit Anti-FPR2 Polyclonal Antibody (MRO-1874-CN) (MRO-1874-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: IF, IHC, FC
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- Species Reactivity: Human
- Application: FC
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For Research Use Only. Not For Clinical Use.