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FZD10
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
Protein class
CD markers, G-protein coupled receptors
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Squamous epithelial cells, Skeletal myocytes, Basal squamous epithelial cells, Smooth muscle cells, Suprabasal keratinocytes, Basal keratinocytes, Fibroblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (AF22, BEWO, hTCEpi, RPTEC TERT1, RT4)
Interaction
Interacts with WNT7B (By similarity). Interacts with MYOC (PubMed:19188438).
Molecular function
Developmental protein, G-protein coupled receptor, Receptor, Transducer
More Types Infomation
- Recombinant Anti-Human FZD10 Antibody scFv Fragment (MOB-2133z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: RIA, ELISA, FuncS
- Recombinant Anti-Human FZD10 Antibody Fab Fragment (MOB-2133z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, IF, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC, ELISA, IF, IP, FC
- Mouse Anti-FZD10 Recombinant Antibody; scFv Fragment (HPAB-0028LY-S(P)) (HPAB-0028LY-S(P))
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- Type: Mouse scFv
- Application: WB
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA, FC, WB, Block
- Anti-Human FZD10 Recombinant Antibody (OTSA101) (TAB-295CL)
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- Species Reactivity: Human
- Type: Antibody
- Application: RIA, IHC
- Mouse Anti-FZD10 Recombinant Antibody (HPAB-0028LY) (HPAB-0028LY)
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- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, WB, Block
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, WB, Block
- Human Anti-FZD10 Recombinant Antibody (VS-0723-WK82) (VS-0723-WK82)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG1
- Application: FC
- Mouse Anti-FZD10 Recombinant Antibody; Fab Fragment (HPAB-0028LY-F(E)) (HPAB-0028LY-F(E))
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- Type: Mouse Fab
- Application: WB
- Human Anti-FZD10 Recombinant Antibody; Fab Fragment (TAB-030CQ-F(E)) (TAB-030CQ-F(E))
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC, WB, Block
- Human Anti-FZD10 Recombinant Antibody; Fab Fragment (TAB-032CQ-F(E)) (TAB-032CQ-F(E))
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, FC, WB, Block
- Human Anti-FZD10 Recombinant Antibody; Fab Fragment (TAB-031CQ-F(E)) (TAB-031CQ-F(E))
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, FC, WB, Block
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For Research Use Only. Not For Clinical Use.