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FZD5
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008]
Protein class
G-protein coupled receptors
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Distal enterocytes, Hepatocytes, Undifferentiated cells, Muller glia cells, Intestinal goblet cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BEWO, CACO-2, Hep G2, NTERA-2)
Interaction
Binding of unsaturated fatty acid molecules (via FZ domain) promotes homodimerization (PubMed:28377511). Interacts with WNT2B (PubMed:12490564). Interacts with WNT7A (PubMed:18230341, PubMed:20530549). Interacts with GOPC (By similarity).
Molecular function
Developmental protein, G-protein coupled receptor, Receptor, Transducer
More Types Infomation
- Human Anti-FZD5 Antibody (clone F2.I), mRNA (PABJ-0145-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib, FuncS
- Human Anti-FZD5 Recombinant Antibody (clone F2.I); Fab fragment (PABJ-0145-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Inhib, FuncS
- Human Anti-FZD5 Recombinant Antibody (clone F2.I); scFv Fragment (PABJ-0145-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Inhib, FuncS
- Rabbit Anti-FZD5 Polyclonal Antibody (MRO-1876-CN) (MRO-1876-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- Species Reactivity: Human
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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