Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Monomer. Interacts with ATG3, ATG7, ATG13 and ULK1 (PubMed:11146101, 11825910, 11096062, 12507496, 23043107). Interacts with TP53INP1 and TP53INP2 (PubMed:19056683, 22421968, 22470510). Interacts with TBC1D25 (PubMed:21383079). Directly interacts with SQSTM1 and BNIP3 (PubMed:17580304, 23209295). Interacts with TECPR2 and PCM1 (PubMed:20562859, 24089205). Interacts with TBC1D5 (PubMed:22354992). Interacts with TRIM5 (PubMed:25127057). Interacts with MEFV and TRIM21 (PubMed:26347139). Interacts with WDFY3 (PubMed:24668264). Interacts with UBA5; promoting recruitment of UBA5 to the endoplasmic reticulum membrane (PubMed:26929408, 30990354). Interacts with GOSR1 (By similarity). Interacts with KBTBD6 AND KBTBD7; the interaction is direct (PubMed:25684205).
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For Research Use Only. Not For Clinical Use.