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GABARAPL2

Enables ubiquitin protein ligase binding activity. Involved in negative regulation of proteasomal protein catabolic process and protein localization to endoplasmic reticulum.
Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Monomer. Interacts with ATG3, ATG7, ATG13 and ULK1 (PubMed:11146101, 11825910, 11096062, 12507496, 23043107). Interacts with TP53INP1 and TP53INP2 (PubMed:19056683, 22421968, 22470510). Interacts with TBC1D25 (PubMed:21383079). Directly interacts with SQSTM1 and BNIP3 (PubMed:17580304, 23209295). Interacts with TECPR2 and PCM1 (PubMed:20562859, 24089205). Interacts with TBC1D5 (PubMed:22354992). Interacts with TRIM5 (PubMed:25127057). Interacts with MEFV and TRIM21 (PubMed:26347139). Interacts with WDFY3 (PubMed:24668264). Interacts with UBA5; promoting recruitment of UBA5 to the endoplasmic reticulum membrane (PubMed:26929408, 30990354). Interacts with GOSR1 (By similarity). Interacts with KBTBD6 AND KBTBD7; the interaction is direct (PubMed:25684205).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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