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GABRD
Gabrd (Gamma-Aminobutyric Acid Type A Receptor Subunit Delta) is a Protein Coding gene. Gamma-aminobutyric acid is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. Diseases associated with Gabrd include Epilepsy, Idiopathic Generalized 10 and Chromosome 1P36 Deletion Syndrome.
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Inhibitory neurons, Excitatory neurons, Bipolar cells, Horizontal cells, Spermatogonia)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (EFO-21, HMC-1, MCF7, NB-4, SH-SY5Y)
Interaction
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.
Molecular function
Chloride channel, Ion channel
More Types Infomation
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- Species Reactivity: Rat
- Type: Mouse antibody
- Application: ICC, WB
- Rabbit Anti-Gabrd Recombinant Antibody (VS-0522-LC105) (VS-0522-LC105)
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- Species Reactivity: Rat, Mouse
- Type: Rabbit IgG
- Application: ICC, WB
- Rat Anti-Gabrd Recombinant Antibody (VS-0522-LC104) (VS-0522-LC104)
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- Species Reactivity: Rat, Mouse
- Type: Rat IgG2b
- Application: ICC, WB
- Rat Anti-Gabrd Recombinant Antibody (clone rtN151/3.3) (VS-0422-LC85)
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- Species Reactivity: Rat, Mouse
- Type: Rat IgG2b
- Application: ICC, WB
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For Research Use Only. Not For Clinical Use.