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GARS
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Cytotrophoblasts, Hofbauer cells, Syncytiotrophoblasts, Cardiomyocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer.
Molecular function
Aminoacyl-tRNA synthetase, Hydrolase, Ligase, Transferase
More Types Infomation
- Rabbit Anti-GARS Recombinant Antibody (clone CBACN-236) (MRO-0634-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, IP, IF, ELISA
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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For Research Use Only. Not For Clinical Use.