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GAS2

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Predicted location

Intracellular

Single cell type specificity

Group enriched (Inhibitory neurons, Excitatory neurons, Oligodendrocytes, Astrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (Hep G2, JURKAT, Karpas-707, SCLC-21H, U-266/84)

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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