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GAS6

This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia.
Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Horizontal cells, Sertoli cells)

Immune cell specificity

Immune cell enriched (plasmacytoid DC)

Cell line specificity

Cell line enhanced (BJ, BJ hTERT+, HSkMC, RPMI-8226)

Interaction

Heterodimer and heterotetramer with AXL.

More Types Infomation

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