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GGH

Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates
GGH
Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Syncytiotrophoblasts, Cytotrophoblasts, Early spermatids, Proximal tubular cells, Extravillous trophoblasts)

Immune cell specificity

Immune cell enriched (plasmacytoid DC)

Cell line specificity

Low cell line specificity

Interaction

Homodimer.

Molecular function

Hydrolase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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