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GIF

This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia.
GIF
Protein class

Disease related genes, Human disease related genes, Metabolic proteins

Predicted location

Secreted

Single cell type specificity

Not detected

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Interacts with CUBN (via CUB domains).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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