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GINS2
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Spermatocytes, Spermatogonia)
Immune cell specificity
Immune cell enhanced (T-reg)
Cell line specificity
Cell line enhanced (U-698)
Interaction
Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4 (PubMed:17417653, PubMed:17545466, PubMed:17557111, PubMed:17652513). Forms a stable subcomplex with GINS3. GINS complex interacts with DNA primase in vitro (PubMed:17417653, PubMed:17545466, PubMed:17557111, PubMed:17652513). Component of the CMG helicase complex, composed of the MCM2-7 complex, the GINS complex and CDC45 (By similarity).
More Types Infomation
- Chicken Anti-GINS2 Polyclonal IgY (BRD-0228MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.