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GIT2
GIT2 (GIT ArfGAP 2) is a Protein Coding gene. This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. Diseases associated with GIT2 include Blind Loop Syndrome and Esophagus Verrucous Carcinoma.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
May forms heterooligomers with GIT1 (By similarity). Directly interacts with protein Piccolo/PCLO (By similarity). Interacts with PPFIA1 and PPFIA2 (By similarity). Interacts with ARHGEF7 (PubMed:10896954). Identified in a complex with ARHGEF6 and BIN2 (PubMed:23285027). Interacts with PAK3 (PubMed:10896954). Interacts with PXN/paxillin (PubMed:11251077). Interacts with TGFB1I1 (By similarity). Forms a complex with EFNB1 and GRB4/NCK2 (By similarity).
Molecular function
GTPase activation
More Types Infomation
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- Species Reactivity: Human
- Application: WB
- Rabbit Anti-GIT2 Recombinant Antibody (clone rN83/48R) (VS-0422-LC93)
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- Species Reactivity: Rat, Human, Mouse
- Type: Rabbit IgG
- Application: IP, WB, IHC
- Human Anti-GIT2 Recombinant Antibody (clone hN83/48R) (VS-0422-LC92)
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- Species Reactivity: Rat, Human, Mouse
- Type: Human IgG1
- Application: IP, WB, IHC
- Rat Anti-GIT2 Recombinant Antibody (clone rtN83/48R) (VS-0422-LC91)
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- Species Reactivity: Rat, Human, Mouse
- Type: Rat IgG2b
- Application: IP, WB, IHC
- Mouse Anti-GIT2 Recombinant Antibody (clone mN83/48R) (VS-0422-LC90)
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- Species Reactivity: Rat, Human, Mouse
- Type: Mouse IgG2a
- Application: IP, WB, IHC
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For Research Use Only. Not For Clinical Use.