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GJA5

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.
GJA5
Protein class

Disease related genes, Human disease related genes, Potential drug targets, Transporters

Predicted location

Membrane

Single cell type specificity

Group enriched (Extravillous trophoblasts, Cytotrophoblasts)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (SK-BR-3)

Interaction

A connexon is composed of a hexamer of connexins.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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