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GJD2

This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion.
GJD2
Protein class

Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Cone photoreceptor cells, Rod photoreceptor cells, Bipolar cells, Horizontal cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (SuSa)

Interaction

A connexon is composed of a hexamer of connexins.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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