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GP9

The glycoprotein (GP)Ib-IX receptor complex plays a critical role in platelet physiology and pathology. Its interaction with von Willebrand factor (VWF) on the subendothelial matrix instigates platelet arrest at the site of vascular injury, and is vital to primary hemostasis.
Protein class

CD markers, Disease related genes, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enriched (Macrophages)

Immune cell specificity

Group enriched (basophil, neutrophil)

Cell line specificity

Cell line enriched (HEL)

Interaction

Two GP-Ib beta are disulfide-linked to one GP-Ib alpha. GP-IX is complexed with the GP-Ib heterodimer via a non covalent linkage.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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