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GPRC5A
Unknown. This G-protein coupled receptor could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. The comparable expression level in fetal lung and kidney with adult tissues suggests a possible role in embryonic development and maturation of these organs. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways
Protein class
G-protein coupled receptors
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Urothelial cells, Alveolar cells type 1, Pancreatic endocrine cells, Distal enterocytes, Paneth cells, Club cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (A-431, A549, CAPAN-2, HaCaT, SiHa)
Interaction
Interacts (via its transmembrane domain) with EGFR.
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: FC, ICC, IHC
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For Research Use Only. Not For Clinical Use.