Disease related genes
Intracellular
Cell type enhanced (Plasma cells, dendritic cells)
Low immune cell specificity
Cell line enhanced (U-2 OS)
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Interacts with TONSL; CHAF1A; CHAF1B; MCM2 and DNAJC9 (PubMed:33857403).
DNA-binding
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For Research Use Only. Not For Clinical Use.