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HOXD13
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Enteroendocrine cells, Basal prostatic cells, Undifferentiated cells, Intestinal goblet cells, Urothelial cells, Prostatic glandular cells, Paneth cells, Distal enterocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HAP1, HEK93, HL-60, JURKAT, NB-4)
Molecular function
Developmental protein, DNA-binding
More Types Infomation
- Recombinant Anti-Human HOXD13 Antibody (MOB-3713z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, FC, FuncS
- Recombinant Anti-Human HOXD13 Antibody scFv Fragment (MOB-3713z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, Neut, FuncS
- Recombinant Anti-Human HOXD13 Antibody Fab Fragment (MOB-3713z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, FuncS
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For Research Use Only. Not For Clinical Use.