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HS6ST1

The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene. [provided by RefSeq, Jul 2008]
Protein class

Disease related genes, Human disease related genes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Granulosa cells, Collecting duct cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (EFO-21, HMC-1, SCLC-21H)

Molecular function

Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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