Intracellular
Group enriched (Spermatocytes, Early spermatids, Spermatogonia, Late spermatids)
Not detected in immune cells
Cell line enhanced (HBEC3-KT)
Associates with HSF2 (PubMed:9651507). The interaction seems to occur between the trimerization domain of HSF2 and the N-terminal hydrophilic region of HSF2BP (PubMed:9651507). Interacts (via C-terminus) with BNC1 (By similarity). Interacts (via N-terminus) with BRCA2 and BRME1; the interactions are direct and allow the formation of a ternary complex. The complex BRME1:HSF2BP:BRCA2 interacts with SPATA22, MEIOB and RAD51 (By similarity) (PubMed:31242413).
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For Research Use Only. Not For Clinical Use.