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HTR7

The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.
Protein class

FDA approved drug targets, G-protein coupled receptors, RAS pathway related proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Inhibitory neurons, Spermatocytes, Early spermatids, Excitatory neurons)

Immune cell specificity

Immune cell enriched (myeloid DC)

Cell line specificity

Cell line enhanced (HBEC3-KT, hTCEpi, hTERT-HME1, LHCN-M2, U-251 MG, U-87 MG, WM-115)

Molecular function

G-protein coupled receptor, Receptor, Transducer

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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