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ICAM2
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Protein class
CD markers, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Adipocytes, Endothelial cells, Hepatic stellate cells, Plasma cells, NK-cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Group enriched (HUVEC TERT2, TIME)
Interaction
Interacts with RDX, EZR and MSN.
More Types Infomation
- Rat Anti-Icam2 Recombinant Antibody (clone 3C4) (NEUT-934CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2a, κ
- Application: IHC-Fr, FC, Block, IP
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- Species Reactivity: Human
- Application: FC, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IF, IP
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ELISA
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IHC-P, IP
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- Species Reactivity: Mouse
- Type: Rat IgG2a, κ
- Application: FC, FuncS, IHC, IP
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For Research Use Only. Not For Clinical Use.