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ICAM3
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms.
Protein class
CD markers, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (NK-cells, T-cells, Hepatocytes, dendritic cells, B-cells, Plasma cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (Karpas-707, NB-4, RPMI-8226, U-266/84, U-937)
Interaction
Interacts with moesin/MSN.
More Types Infomation
- Mouse Anti-ICAM3 Recombinant Antibody (clone CBL306) (NEUT-940CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Block, WB
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Block, CyTOF, FC, WB
- Mouse Anti-ICAM3 Recombinant Antibody (clone SPM505) (NEUT-938CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: IHC-P, IF, ICC, FC, Block
- Mouse Anti-ICAM3 Recombinant Antibody (clone 8V23) (NEUT-937CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut, WB
-
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: ICC, IF, FC, Block, IHC-P
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC, ICC, IP, WB
-
- Species Reactivity: Human
- Application: IHC-P, WB
- Recombinant Human Anti-human ICAM3 Antibody Fab Fragment (MHH-534-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: WB, ELISA, IHC, FuncS
- Recombinant Human Anti-human ICAM3 Antibody scFv Fragment (MHH-534-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, IF, FuncS
- Recombinant Anti-human ICAM3 Antibody scFv Fragment (MOB-534-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
- Recombinant Anti-human ICAM3 Antibody Fab Fragment (MOB-534-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: Neut, IF, FuncS
- Recombinant Anti-human ICAM3 Antibody (MOB-534)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC, FuncS
- Mouse Anti-ICAM3 Recombinant Antibody (clone CBL020) (NEUT-935CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut, WB
- Human Anti-ICAM3 Recombinant Antibody (clone CG106) (FAMAB-1196CQ)
-
- Species Reactivity: Human
- Type: Human IgG1
- Application: FACS, IP, WB, IHC
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: IF, ELISA, FuncS
- Anti-Human ICAM-3 Recombinant Antibody Fab Fragment (IB23) (TAB-127CT-F(E))
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- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
-
- Derivation: Chimeric (human/mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Anti-Human ICAM3 Recombinant Antibody (TAB-377CL)
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- Derivation: Chimeric (human/mouse)
- Species Reactivity: Human
- Type: Antibody
- Human Anti-ICAM3 Recombinant Antibody; Fab Fragment (clone huICR-8.1) (HPAB-1603WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, FC
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For Research Use Only. Not For Clinical Use.