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IER3IP1
This gene encodes a small protein that is localized to the endoplasmic reticulum (ER) and may play a role in the ER stress response by mediating cell differentiation and apoptosis. Transcription of this gene is regulated by tumor necrosis factor alpha and specificity protein 1 (Sp1). Mutations in this gene may play a role in microcephaly, epilepsy, and diabetes syndrome (MEDS), and a pseudogene of this gene is located on the long arm of chromosome 12.
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Proximal tubular cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: FC, IHC-P, WB, ICC, IF, IP
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For Research Use Only. Not For Clinical Use.