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IFITM1
IFITM1 (Interferon Induced Transmembrane Protein 1) is a Protein Coding gene. Diseases associated with IFITM1 include Influenza and West Nile Virus. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. Gene Ontology (GO) annotations related to this gene include signal transducer activity, downstream of receptor. An important paralog of this gene is IFITM3.
Protein class
CD markers, Plasma proteins, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Basal squamous epithelial cells, T-cells, Endothelial cells, Leydig cells, Sertoli cells)
Immune cell specificity
Group enriched (NK-cell, memory CD4 T-cell, memory CD8 T-cell, naive CD8 T-cell, naive CD4 T-cell, gdT-cell, neutrophil, MAIT T-cell, T-reg, eosinophil)
Cell line specificity
Cell line enhanced (BJ hTERT+, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, HMC-1)
Interaction
Interacts with CD81 (PubMed:2398277, PubMed:26354436). Part of a complex composed of CD19, CR2/CD21, CD81 and IFITM1/CD225 in the membrane of mature B-cells (PubMed:1383329). Interacts with CAV1; this interaction enhances the ability of CAV1 in inhibiting ERK activation (PubMed:19499152).
More Types Infomation
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ELISA, FC, IF, IHC, IP
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF, IP
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For Research Use Only. Not For Clinical Use.