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IGF2R
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate.
Protein class
Cancer-related genes, CD markers, Plasma proteins, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (NK-cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Low cell line specificity
Interaction
Binds HA-I and HA-II plasma membrane adapters (By similarity). Interacts with DPP4; the interaction is direct. Binds GGA1, GGA2 and GGA3. Interacts with the heterotrimeric retromer cargo-selective complex (CSC), formed by VPS26 (VPS26A or VPS26B), VPS29 and VPS35; which is involved in retrograde trafficking of the receptor from endosomes to the Golgi apparatus (Probable).
Molecular function
Receptor
More Types Infomation
- Mouse Anti-IGF2R Recombinant Antibody (clone 2G11) (NEUT-1084CQ)
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- Species Reactivity: Human, Fruit fly, Rat, Hamster, Primate, Rabbit, Bovine, Invertebrate
- Type: Mouse IgG2a
- Application: Block, FC, ICC, IF, IHC, IP, WB
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, ICC, IP, FC
- Rabbit Anti-IGF2R Polyclonal Antibody (MRO-1958-CN) (MRO-1958-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, IHC, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, FC, ICC, IF, IHC, IP
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- Species Reactivity: Human
- Application: FC
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- Type: Mouse IgG1
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP, FC
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For Research Use Only. Not For Clinical Use.