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IGFBP6
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Protein class
Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Group enriched (Peritubular cells, Fibroblasts, Sertoli cells, Leydig cells, Basal respiratory cells, Smooth muscle cells)
Immune cell specificity
Immune cell enhanced (eosinophil, non-classical monocyte)
Cell line specificity
Cell line enhanced (ASC TERT1, BJ, BJ hTERT+, fHDF/TERT166, hTERT-RPE1, U-87 MG)
Interaction
Interacts (via C-terminal domain) with PHB2.
Molecular function
Growth factor binding
More Types Infomation
- Recombinant Mouse Anti-Human IGFBP6 Antibody (MOB-2257MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, WB
- Mouse Anti-IGFBP6 Recombinant Antibody (clone CBL576) (NEUT-1096CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: Neut
- Mouse Anti-IGFBP6 Recombinant Antibody (clone CBL081) (NEUT-1095CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2
- Application: Neut, WB
- Mouse Anti-IGFBP6 Recombinant Antibody (clone 9L21) (NEUT-1094CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2
- Application: Neut, WB
- Chicken Anti-IGFBP6 Polyclonal IgY (BRD-0273MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.