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IK

The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Respiratory ciliated cells, Endometrial ciliated cells, Early spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

(Microbial infection) Identified in a complex with SMU1 and influenza A virus RNA polymerase subunits PB1 and PB2. Directly interacts with SMU1 and with influenza A virus RNA polymerase subunits PB1 and PB2. Component of the spliceosome B complex (PubMed:22365833, PubMed:28781166). Interacts with SMU1 (PubMed:22365833, PubMed:24945353). Interacts with MAD1L1 (PubMed:22351768). May interact with DHX15 (PubMed:24252166).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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