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IKZF4

Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Immune cell enriched (T-reg)

Cell line specificity

Cell line enhanced (HDLM-2)

Interaction

Self-associates. Interacts with other family members; IKZF1, IKZF2, IKZF3 and IKZF5. Interacts with CTBP2. Interacts with SPI1, MITF, FOXP3 and CTBP1 (By similarity).

Molecular function

DNA-binding, Repressor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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