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IL10RB
The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq, Jul 2008]
Protein class
CD markers, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Cytotrophoblasts, Extravillous trophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Heterodimer with IFNLR1.
Molecular function
Receptor
More Types Infomation
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, WB, Neut
- Mouse Anti-IL10RB Recombinant Antibody (clone CBL507) (NEUT-1140CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, CyTOF, Neut
- Mouse Anti-IL10RB Recombinant Antibody (clone CBL077) (NEUT-1139CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut, WB
-
- Species Reactivity: Human
- Application: Neut, WB
-
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
-
- Type: Mouse IgG1
- Application: ELISA, ICC, FC
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For Research Use Only. Not For Clinical Use.