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IL17D

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.
Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Astrocytes, Late spermatids, Oligodendrocyte precursor cells, Muller glia cells, Early spermatids, Excitatory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (TIME)

Molecular function

Cytokine

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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