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INMT
N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream FAM188B (family with sequence similarity 188, member B) gene.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Group enriched (Peritubular cells, Leydig cells, Hepatic stellate cells, Endothelial cells)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Group enriched (CACO-2, HHSteC)
Interaction
Monomer.
Molecular function
Methyltransferase, Transferase
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, FC
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For Research Use Only. Not For Clinical Use.