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IRX1

This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13.
Protein class

Plasma proteins, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Group enriched (Breast myoepithelial cells, Breast glandular cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, REH, U-251 MG)

Molecular function

DNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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