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IRX3

IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Breast glandular cells, Glandular and luminal cells, Breast myoepithelial cells, Endometrial ciliated cells, Squamous epithelial cells, Respiratory ciliated cells, Alveolar cells type 2)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (LHCN-M2, NB-4, RPTEC TERT1, T-47d, THP-1)

Molecular function

Developmental protein, DNA-binding, Repressor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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