ITGA2B
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]
Derivation: Human
Species Reactivity: Human
Type: Human Fab
Application: Block
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Species Reactivity: Human
Type: Rabbit IgG
Application: WB, IHC
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Derivation: Human
Species Reactivity: Human
Type: Human IgG
Application: Block
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Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG1
Application: FC, IHC, FuncS
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Derivation: Human
Species Reactivity: Human
Type: Human scFv
Application: Block
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Species Reactivity: Human
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Derivation: Phage display library screening
Species Reactivity: Human
Type: IgG
Application: WB, IHC
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Species Reactivity: Human
Type: Mouse antibody
Application: WB, IP, FC
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Species Reactivity: Human
Type: IgM, κ
Application: FC, IP, WB, BL
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Species Reactivity: Human
Type: IgG2a, κ
Application: FC, BL, IP
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Species Reactivity: Human, Rhesus, Cynomolgus, Pig, Baboon, Capuchin Monkey, Chimpanzee
Type: IgG1, κ
Application: CyTOF, FuncS, FC, IFC, IHC, Neut
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Species Reactivity: Human, Mouse, Rat
Type: Mouse IgG
Application: WB, IHC
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Derivation: Humanized
Species Reactivity: Human, Mouse, Rat
Type: Humanized IgG
Application: FuncS
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Species Reactivity: Human
Type: Mouse IgG1, κ
Application: FuncS
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Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG
Application: ELISA, IHC
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Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG1
Application: FC, IF
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Species Reactivity: Human
Type: Mouse IgG1, κ
Application: IF
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Species Reactivity: Mouse
Type: Rat IgG1, κ
Application: FC, FuncS, IHC-Fr, IF, IP, IHC
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Species Reactivity: Human
Type: Mouse IgG
Application: ELISA, FuncS
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Derivation: Humanized
Species Reactivity: Human, Mouse, Rat
Type: Humanized Fab
Application: FuncS
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For Research Use Only. Not For Clinical Use.