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ITGA9
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.
Protein class
Human disease related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Excitatory neurons, Peritubular cells, Inhibitory neurons, Hepatic stellate cells, Microglial cells, Leydig cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (CACO-2, HEL, SH-SY5Y, SuSa, WM-115)
Interaction
Heterodimer of an alpha and a beta subunit. Alpha-9 (ITGA9) associates with beta-1 (ITGB1). Integrin ITGA9:ITGB1 interacts with FBLN5 (via N-terminus).
Molecular function
Integrin, Receptor
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, IHC-P
- Human Anti-ITGA9 Recombinant Antibody; scFv Fragment (HPAB-1273-FY-S(P)) (HPAB-1273-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Human Anti-ITGA9 Recombinant Antibody (HPAB-1274-FY) (HPAB-1274-FY)
-
- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: ELISA
- Human Anti-ITGA9 Recombinant Antibody (HPAB-1273-FY) (HPAB-1273-FY)
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody (HPAB-1272-FY) (HPAB-1272-FY)
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody; Fab Fragment (HPAB-1272-FY-F(E)) (HPAB-1272-FY-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody; Fab Fragment (HPAB-1271-FY-F(E)) (HPAB-1271-FY-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody; Fab Fragment (HPAB-1270-FY-F(E)) (HPAB-1270-FY-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody; Fab Fragment (HPAB-1269-FY-F(E)) (HPAB-1269-FY-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody; scFv Fragment (HPAB-1272-FY-S(P)) (HPAB-1272-FY-S(P))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody; scFv Fragment (HPAB-1271-FY-S(P)) (HPAB-1271-FY-S(P))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody; scFv Fragment (HPAB-1270-FY-S(P)) (HPAB-1270-FY-S(P))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody; scFv Fragment (HPAB-1269-FY-S(P)) (HPAB-1269-FY-S(P))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody (HPAB-1271-FY) (HPAB-1271-FY)
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody (HPAB-1270-FY) (HPAB-1270-FY)
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody (HPAB-1269-FY) (HPAB-1269-FY)
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Human Anti-ITGA9 Recombinant Antibody; Fab Fragment (HPAB-0833-CN-F(E)) (HPAB-0833-CN-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
- Mouse Anti-ITGA9 Recombinant Antibody; Fab Fragment (TAB-740LC-F(E)) (TAB-740LC-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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