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ITGAX

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.
Protein class

CD markers, FDA approved drug targets

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Macrophages, Langerhans cells, granulocytes, NK-cells, Microglial cells, Kupffer cells, Alveolar cells type 2, Hofbauer cells)

Immune cell specificity

Immune cell enhanced (neutrophil)

Cell line specificity

Cell line enriched (HMC-1)

Interaction

Heterodimer of an alpha and a beta subunit. Alpha-X associates with beta-2.

Molecular function

Integrin, Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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