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JAG2

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged2 is one of several ligands that activate Notch and related receptors.
Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Adipocytes, Endothelial cells, Basal respiratory cells, Basal squamous epithelial cells, Horizontal cells, Breast myoepithelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HaCaT, HBEC3-KT, SCLC-21H)

Molecular function

Developmental protein

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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