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JAM3

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.
Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular, Membrane, Secreted (different isoforms)

Single cell type specificity

Cell type enriched (Oligodendrocytes)

Immune cell specificity

Immune cell enhanced (memory B-cell)

Cell line specificity

Cell line enhanced (HUVEC TERT2, RH-30)

Interaction

Interacts with ITGAM (PubMed:12208882, 15194813). Interacts with GORASP2 (By similarity).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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