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JAML
AMICA1 (Adhesion Molecule, Interacts With CXADR Antigen 1) is a Protein Coding gene. Among its related pathways are Immune System and Hemostasis. GO annotations related to this gene include protein homodimerization activity and cell adhesion molecule binding.
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Group enriched (monocytes, Macrophages, dendritic cells, Kupffer cells, T-cells)
Immune cell specificity
Immune cell enhanced (eosinophil)
Cell line specificity
Cell line enriched (HMC-1)
Interaction
Homodimer; active form in leukocyte-endothelial cell adhesion. Interacts (homodimeric form) with CXADR. Interacts (via cytoplasmic domain) with the PI3 kinase; upon CXADR-binding. Interacts with ITGA4 and ITGB1; integrin alpha-4/beta-1 may regulate leukocyte to endothelial cells adhesion by controlling JAML homodimerization.
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: FC, WB, IP
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- Derivation: Mouse
- Species Reactivity: Mouse
- Type: Mouse IgG
- Application: FACS, IP, SPR, FC, IF
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- Derivation: Mouse
- Species Reactivity: Mouse
- Type: Mouse scFv
- Application: FACS, IP, SPR, FC, IF
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- Derivation: Mouse
- Species Reactivity: Mouse
- Type: Mouse Fab
- Application: FACS, IP, SPR, FC, IF
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For Research Use Only. Not For Clinical Use.