Loading...
JUNB
JUNB (JunB Proto-Oncogene, AP-1 Transcription Factor Subunit) is a Protein Coding gene. Diseases associated with JUNB include Anaplastic Large Cell Lymphoma and Fumarate Hydratase Deficiency. Among its related pathways are ERK Signaling and Gene Expression. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcription factor binding. An important paralog of this gene is JUN.
Protein class
Human disease related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (HDLM-2, U-266/70, U-266/84)
Interaction
Binds DNA as a homodimer or as a heterodimer with another member of the Jun/Fos family. Component of an AP-1 transcription factor complex composed of JUN-FOS heterodimers composed of JUN-FOS heterodimers (By similarity). As part of the AP-1 transcription factor complex, forms heterodimers with FOSB, thereby binding to the AP-1 consensus sequence and stimulating transcription (By similarity). Interacts with ITCH (via its WW domains).
Molecular function
DNA-binding
More Types Infomation
Related Signaling Pathways
TNF Signaling Pathway
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IP
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, ICC, IP
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
-
- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, ICC, FC, ChIP
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IP
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IP
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC, IF
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.